Vacuum nutsche filter dryer supplier from China: In the production process of AIPs, in order to reduce the material loss and avoid environment pollution that may be caused by the material transfer after crystallization, the subsequent filtration, washing and drying processes of the material are usually completed in one single piece of equipment, which is called Three-in-One; for short or Agitated Nutsche Filter Dryer(ANFD). The most common Three-in-One used in drug production is with flat bottom, and there is no doubt that it has advantages in the production of sterile APIs, however, certain defects in another side as well, including small filter area in the circular flat bottom, side discharge (there is always material left behind), poor drying performance, small movement of material during the drying process, and low efficient heat transfer, more limits of drying, etc. See more details on agitated filter dryer.
The stirring device is usually a mechanical paddle or impeller that is driven by an external motor and connected to the reactor wall. This creates agitation within the tank by circulatory motion, which helps homogenize the materials much more quickly than traditional open systems. As a result, reactions between different components occur more rapidly and at lower temperatures than in other reactors, saving energy and increasing efficiency. The CSTR also offers superior safety compared to other reactors due to its closed-system design. In addition, this type of reactor can be operated at higher pressures than open systems, allowing for better control over reaction conditions and greater product yields.
Our technical team is composed of engineers in various fields, including quality assurance, process, equipment, welding, and electrics, and most of them have working experience and engineering project experience of more than ten years. For inflammable, explosive, toxic and corrosive products in pharmaceutical, fine chemical, pesticide, and new energy industries, we will provide customized technical solutions to clients with well-sealed, high vacuum and fully automatic equipment, ensuring safe, energy saving and environment protecting production process, compliance with EHS requirements.
Wuxi Zhanghua Pharmaceutical Equipment Co.,Ltd was founded in 1976, committed to researching, developing and manufacturing reaction, crystallization, filtration, drying equipment. With the development of the leading technologies for more than 40 years, our engineering equipment is not only for the pharmaceutical industry, but also for fine chemicals, pesticides, new energy, new materials and other industries. We customize the integrated solution of reaction, crystallization, filtration and drying process equipment for clients.
The Agitated Nutsche Filter is a closed vessel that separates solids from liquids using filtration under pressure or vacuum. The closed system maintains product quality and hygiene by providing odourless, contaminant-free and pollution-free working conditions. Agitated Nutsche filters are used in the chemical, herbal, pharmaceutical, agrochemical and food industries. From a process point of view, Nutsche filters/dryers have a relatively wide range of uses; although they are commonly used to recover solid materials in a few cases. Filling/charging, filtration, displacement washing, slurry washing, smoothing, drying/cooling, and discharging are all tasks that can be performed by modern suction filters. Discover more information at https://www.filter-dryer.com/.
Zhanghua is a renowned manufacturer of world-class pharmaceutical equipment, including high-quality stainless steel reaction kettles. Our reactor tanks are designed and engineered to meet the most demanding industrial requirements, offering exceptional performance, reliability, and durability. Our stainless steel reactors are made from premium-grade materials that offer superior resistance to corrosion, abrasion, and other forms of wear and tear. They feature a robust construction that can withstand extreme temperatures and pressures, making them ideal for a wide range of applications in the chemical, pharmaceutical, and food industries.
The mixer operates by rotating the V-shaped container on its axis. The rotation causes the materials to move in a complex motion, which includes rolling, cascading, and crossing over each other. As a result, the materials are constantly being intermixed and distributed evenly throughout the container. V type blenders are known for their versatility and ability to handle a wide range of materials, including powders, granules, pastes, and viscous liquids. They are particularly effective at blending materials with different particle sizes and densities. The mixing process can be further enhanced by incorporating additional features such as intensifier bars or choppers to break up agglomerates or lumps.
During the process, adjust the stirring speed by the agitator, keep stirring the material, and remain in a state of vacuum and constant temperature (acceptable temperature of the material) until the humidity of the material reaches the requirement. After drying, the material needs to be cooled to appreciate temperature before discharge. Discharge: The dried and cooled product is delivered to a tank, a container, or the transport system by gravity from a discharge valve at the bottom with the assistance of the spiral shaft and stirring arm to maintain a high output without residuals left behind. Overall, Wuxi Zhanghua’s single conical vacuum dryer combines efficient drying capabilities with safety, flexibility, and ease of use.
